Which statement best differentiates the somatic and autonomic nervous systems?

Somatic controls glands; Autonomic controls skeletal muscles

Somatic is involuntary; Autonomic is voluntary

Somatic targets smooth muscle only; Autonomic targets skeletal muscle only

Somatic controls voluntary skeletal muscles; Autonomic controls involuntary smooth/cardiac muscle and glands

At its heart, this differentiates voluntary control of skeletal muscles from involuntary regulation of other tissues. The somatic system carries voluntary motor commands from the central nervous system to skeletal muscles, enabling conscious movements. The autonomic system operates largely outside conscious control, regulating involuntary functions by acting on smooth muscle, cardiac muscle, and glands. Functionally, somatic pathways use a single motor neuron from the CNS to the skeletal muscle at the neuromuscular junction, while autonomic pathways involve a two-neuron chain (preganglionic and postganglionic) targeting smooth or cardiac muscle and glands, with divisions like sympathetic and parasympathetic influencing the responses. So, the statement that somatic controls voluntary skeletal muscles and autonomic controls involuntary smooth/cardiac muscle and glands captures the core distinction.

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